Michael Clark, Christina Nguyen, Hung Nguyen, Aidan Tay, Samuel J. Beach, Maciej Maselko, Victor Lopez Del Amo
Expanding the CRISPR base editing toolbox in Drosophila melanogaster
Communications Biology, 2024 September 12; 7(1), 1126.
Travis C Collier, Yoosook Lee, Derrick K. Mathias, Victor Lopez Del Amo
CRISPR-Cas9 and Cas12a Target Site Richness Reflects Genomic Diversity in natural populations of Anopheles gambiae and Aedes aegypti mosquitoes
BMC Genomics, 2024 July 25;700
Sara Sanz Juste, Emily M. Okamoto, Christina Nguyen, Xuechun Feng, Victor Lopez del Amo
Next-generation CRISPR gene-drive systems using Cas12a nuclease
Nature Communications, 2023 October 12; 14(1), 6388.
Sitara Roy, Sara Sanz Juste, Marketta Sneider, Carissa Clanseck, Zhiqian Li, Alison Henrique Ferreira, Victor Lopez del Amo, Ethan Bier, Annabel Guichard
Cas9/nickase-induced allelic conversion by homologous chromosome-templated in Drosophila somatic cells
Science Advances, 2022 July 1; 8(26) eabo0721
López del Amo V*, Sara Sanz Juste, Valentino Gantz*
A nickase Cas9 gene-drive system promotes super-Mendelian inheritance in Drosophila
Cell Reports, 2022 May 24;39(8):110843.
*corresponding authors
Alena Bishop, López del Amo V, Emily Okamoto , Zsolt Bodai, Alexis Komor, Valentino M Gantz
Double-Tap Gene Drive: iterative genome targeting helps overcome resistance alleles
Nature Communications, 2022 May 9;13(1):2595.
Andrea Tapia-González, Martina Palomino-Schätzlein, Marta Roca, Agustín Lahoz, Antonio Pineda-Lucena,
López del Amo V*, Máximo Ibo Galindo*
Mild muscle mitochondrial fusion distress extends Drosophila lifespan through an early and systemic metabolome reorganization
Int. J. Mol. Sci., 2021, 22, 12133
*corresponding authors
Xuechun Feng, López Del Amo V, Enzo Mameli, Megan Lee, Alena L. Bishop, Norbert Perrimon,VM. Gantz.
Optimized CRISPR tools and site-directed transgenesis in Culex quinquefasciatus mosquitoes for gene drive development.
Nature Communications, 2021 May 20;12(1):2960.
López del Amo V, Brittany S. Leger, Kurt J. Cox, Shubhroz Gill, Alena L. Bishop, Garrett D. Scanlon, James A. Walker, Valentino M. Gantz, Amit Choudhary.
Small-molecule control of super-Mendelian inheritance in gene drives.
Cell Reports, 2020 Jun 30;31(13):107841.
Wolf C*, López Del Amo V*, Arndt S, Bueno D, Tenzer S, Hanschmann EM, Berndt C, Methner A.
Redox Modifications of Proteins of the Mitochondrial Fusion and Fission Machinery.
Cells (Review), 2020 Mar 27;9(4). pii: E815.
*co-first authors
López Del Amo V, Bishop AL, Sánchez C HM, Bennett JB, Feng X, Marshall JM, Bier E, Gantz VM.
A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment.
Nature Communications, 2020 Jan 17;11(1):352.
Calpena E, López del Amo V, Chakraborty M, Llamusí B, Artero R, Espinós C, Galindo Orozco MI.
The Drosophila junctophilin gene is functionally equivalent to its four mammalian counterparts and is a modifier of a Huntingtin poly-Q expansion and the Notch pathway.
Disease Models and Mechanisms, 2018 Jan 17;11(1). pii: dmm029082.
López del Amo V*, Palomino-Schätzlein M*, Seco-Cervera M, García-Giménez JL, Pallardó F, Pineda Lucena A, Galindo Orozco MI.
A Drosophila model of GDAP1 function links mitochondrial dynamics to insulin signaling in Charcot-Marie-Tooth neuropathy.
Biochim Biophys Acta (BBA)- Molecular Basis of Disease. 2017 Mar;1863(3):801-809.
*co-first authors
López del Amo V, Seco-Cervera M, García Giménez JL, Withworth AJ, Pallardó F, Galindo MI. Mitochondrial defects and neuromuscular degeneration caused by altered expression of Drosophila Gdap1: implications for the Charcot-Marie-Tooth neuropathy.
Human Molecular Genetics. 2015 Jan 1;24(1):21-36.
Expanding the CRISPR base editing toolbox in Drosophila melanogaster
Communications Biology, 2024 September 12; 7(1), 1126.
Travis C Collier, Yoosook Lee, Derrick K. Mathias, Victor Lopez Del Amo
CRISPR-Cas9 and Cas12a Target Site Richness Reflects Genomic Diversity in natural populations of Anopheles gambiae and Aedes aegypti mosquitoes
BMC Genomics, 2024 July 25;700
Sara Sanz Juste, Emily M. Okamoto, Christina Nguyen, Xuechun Feng, Victor Lopez del Amo
Next-generation CRISPR gene-drive systems using Cas12a nuclease
Nature Communications, 2023 October 12; 14(1), 6388.
Sitara Roy, Sara Sanz Juste, Marketta Sneider, Carissa Clanseck, Zhiqian Li, Alison Henrique Ferreira, Victor Lopez del Amo, Ethan Bier, Annabel Guichard
Cas9/nickase-induced allelic conversion by homologous chromosome-templated in Drosophila somatic cells
Science Advances, 2022 July 1; 8(26) eabo0721
López del Amo V*, Sara Sanz Juste, Valentino Gantz*
A nickase Cas9 gene-drive system promotes super-Mendelian inheritance in Drosophila
Cell Reports, 2022 May 24;39(8):110843.
*corresponding authors
Alena Bishop, López del Amo V, Emily Okamoto , Zsolt Bodai, Alexis Komor, Valentino M Gantz
Double-Tap Gene Drive: iterative genome targeting helps overcome resistance alleles
Nature Communications, 2022 May 9;13(1):2595.
Andrea Tapia-González, Martina Palomino-Schätzlein, Marta Roca, Agustín Lahoz, Antonio Pineda-Lucena,
López del Amo V*, Máximo Ibo Galindo*
Mild muscle mitochondrial fusion distress extends Drosophila lifespan through an early and systemic metabolome reorganization
Int. J. Mol. Sci., 2021, 22, 12133
*corresponding authors
Xuechun Feng, López Del Amo V, Enzo Mameli, Megan Lee, Alena L. Bishop, Norbert Perrimon,VM. Gantz.
Optimized CRISPR tools and site-directed transgenesis in Culex quinquefasciatus mosquitoes for gene drive development.
Nature Communications, 2021 May 20;12(1):2960.
López del Amo V, Brittany S. Leger, Kurt J. Cox, Shubhroz Gill, Alena L. Bishop, Garrett D. Scanlon, James A. Walker, Valentino M. Gantz, Amit Choudhary.
Small-molecule control of super-Mendelian inheritance in gene drives.
Cell Reports, 2020 Jun 30;31(13):107841.
Wolf C*, López Del Amo V*, Arndt S, Bueno D, Tenzer S, Hanschmann EM, Berndt C, Methner A.
Redox Modifications of Proteins of the Mitochondrial Fusion and Fission Machinery.
Cells (Review), 2020 Mar 27;9(4). pii: E815.
*co-first authors
López Del Amo V, Bishop AL, Sánchez C HM, Bennett JB, Feng X, Marshall JM, Bier E, Gantz VM.
A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment.
Nature Communications, 2020 Jan 17;11(1):352.
Calpena E, López del Amo V, Chakraborty M, Llamusí B, Artero R, Espinós C, Galindo Orozco MI.
The Drosophila junctophilin gene is functionally equivalent to its four mammalian counterparts and is a modifier of a Huntingtin poly-Q expansion and the Notch pathway.
Disease Models and Mechanisms, 2018 Jan 17;11(1). pii: dmm029082.
López del Amo V*, Palomino-Schätzlein M*, Seco-Cervera M, García-Giménez JL, Pallardó F, Pineda Lucena A, Galindo Orozco MI.
A Drosophila model of GDAP1 function links mitochondrial dynamics to insulin signaling in Charcot-Marie-Tooth neuropathy.
Biochim Biophys Acta (BBA)- Molecular Basis of Disease. 2017 Mar;1863(3):801-809.
*co-first authors
López del Amo V, Seco-Cervera M, García Giménez JL, Withworth AJ, Pallardó F, Galindo MI. Mitochondrial defects and neuromuscular degeneration caused by altered expression of Drosophila Gdap1: implications for the Charcot-Marie-Tooth neuropathy.
Human Molecular Genetics. 2015 Jan 1;24(1):21-36.